产品货号：
Z29001
中文名称：
UPF3B抗体
英文名称：
Anti-UPF3B Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-UPF3B Antibody |
| 指标别名 | HUPF3B,hUpf3p X,MRXS14,RENT3B,UPF3B,UPF3X |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | UPF3B |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human UPF3B/RENT3B (416-452aa SEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSRNRL). |
| 实际分子量 | 58KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Regulator of nonsense transcripts 3B is a protein that in humans is encoded by the UPF3B gene.This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance.The encoded protein is one of two functional homologs to yeast Upf3p.mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD).When translation ends upstream from the last exon-exon junction,this triggers NMD to degrade mRNAs containing premature stop codons.This protein binds to the mRNA and remains bound after nuclear export,acting as a nucleocytoplasmic shuttling protein.It forms with Y14 a complex that binds specifically 20nt upstream of exon-exon junctions.This gene is located on the long arm of chromosome X.Two splice variants encoding different isoforms have been found for this gene. |
| Uniprot ID | Q9BZI7 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | UPF3 regulator of nonsense transcripts homolog B (yeast) |
| 蛋白名全称 | Regulator of nonsense transcripts 3B |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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